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Kiora Pharmaceuticals, specialises in ophthalmology, developing treatment therapies for eye diseases. They have received approval for their new drug, KIO-101, to enter a Phase 2 study. The drug therapy focuses on treating the Ocular Presentation of Rheumatoid Arthritis and additional autoimmune diseases. The drug is a DHODH inhibitor, administered through eye drops, to reduce T-cell proliferation and ongoing proinflammatory cytokine release. Around 3.43 million patients in the U.S. suffer from the immune diseases that KIO-101 targets, all are caused by ocular manifestations.
Eric Daniels, M.D., Chief Development Officer of Kiora said: “KIO-101 is a topical, patient-friendly eye drop with a proven mechanism of action in autoimmune diseases. Proof-of-concept has been established in previous ocular inflammation clinical studies for KIO-101. This drug has the potential to finally close the wide gap of untreated ocular disease in patients with common autoimmune diseases.”